Rotor syndrome
HepatologyRotor syndrome is classified as a rare inherited disease in which bilirubin metabolism is impaired and red blood cells are destroyed.
Treatment methods
An important part in the therapy is a diet aimed at reducing the accumulation of bilirubin in the body. Patients should exclude spicy and fatty foods. Patients should also limit alcohol consumption.
Specialists often prescribe medications – choleretic medications – that can help lower bilirubin levels and reduce symptoms of jaundice and hearing.
Patients with the disease have a problem with the transportation and excretion of bilirubin from the liver. Thus it accumulates in the body. This accumulated component gives a jaundiced skin tone.
The main sign of the disease is increased indirect bilirubin in the blood. It does not bind to acid and therefore is not excreted with bile.
Jaundice is the most characteristic symptom of the disease. Patients develop a yellowish tint to the whites of the eyes. Sometimes there may be discomfort or pain in the abdominal area due to an enlarged liver.
The syndrome is an inherited condition and usually manifests in childhood or adolescence. It is important to note that this is a chronic condition and treatment is aimed at reducing symptoms and maintaining the patient’s quality of life.
Diagnosis is made based on scientific signs as well as genetic and laboratory tests. Patients with this syndrome usually require regular follow-up with a physician and diet.
Diagnosis at MDI Clinic
The specialist examines the patient, discusses the patient’s private and family history, and gives a number of symptoms characteristic of the disease. Genetic tests are performed to make a definitive diagnosis. These tests analyze the genes associated with these genetic diseases, SLCO1B1 and SLCO1B3. Finding mutations helps to make a diagnosis.
Increased size of the liver and spleen are the main symptoms of the disease. Abdominal ultrasound assesses the condition of internal organs.
Magnetic resonance device allows you to visualize the bile ducts and assess their condition. It can be used to rule out other biliary pathologies.
The best doctors in Israel
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Dr. Alex Geller
Hepatologist
Gastroenterologist
Endoscopist -
Prof. Ran Oren
Gastroenterologist
Hepatologist -
Dr. Ricky Shapira
Gastroenterologist
Hepatologist -
Dr. Aryeh ARISH
Hepatobiliary surgeon
Hepatologist -
Prof. Rafael BROOK
Gastroenterologist
Hepatologist -
Prof. Oren Chibollet
Hepatologist
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Prof. Ziv BEN-ARI
Hepatologist
Price
How we are working
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StepSubmitting an application
Simply leave a request or contact us at the numbers in the contact tab.
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StepTalking to a counselor
You will be contacted by our consultant shortly after submitting your application. After the interview and review of the medical history, he will proceed to prepare a treatment program.
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StepProgram preparation
Our specialists will draw up a personalized program, including a diagnosis and treatment schedule, the names and positions of the doctors, and the cost of treatment.
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StepTravel arrangements
The coordinator will plan and organize the trip in every detail – from advice on preparing documents, to purchasing tickets, booking accommodation and even organizing excursions.
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StepTreatment
Our staff will provide patient support throughout the diagnosis, treatment and rehabilitation period.
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Really enjoyed the MDI clinic. Great attitude towards patients. Applied with the problem of psoriasis (>10 years trying to cure and nothing helps). I was worried about how everything would go, as I was flying from another country, but before arrival everything was discussed with me: what to do, how much time of stay will be needed, cost, accommodation, absolutely everything and I was not so worried. Upon arrival I was met, driven to the hotel and was in constant contact with me. Also gave a local SIM card for communication and internet, drove and accompanied everywhere. Was in Tel Aviv for 3 days and during this time visited the doctor, did all the necessary tests and prescribed treatment. After leaving, I am still in touch with the curators and doctors to find out how the treatment is going, whether the medication is helping, my general health, whether I need to send more medication, etc. I am very glad that I visited MDI clinic, as it was the first time I saw the effect of treatment and that it actually helps. Words can't describe the emotions and feelings when you realize that you will finally be healthy and you can no longer be self-conscious about your skin, wear open clothes, put your hair up however you want, etc. -
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We thank you from the bottom of our hearts for your concern. From the first contact to the last minute of being in Israel, we constantly felt cared for. Meeting at the airport, organization of accommodation, support during the quarantine, useful household advice, help in buying food, accompaniment to procedures and consultations with doctors, help in buying medicines, a clear plan of action and constant information about the progress of treatment - our stay in Tel Aviv was so competently organized that the whole treatment took place in an atmosphere of confidence, calmness and relaxation. There was no stress of being in another country, even though the reason for coming to Israel was not a fun one - my father's metastatic prostate cancer. Special thanks to Catherine, for her heartfelt attitude and involvement with us. Thank you so much! Success, prosperity and grateful patients!